Chemo Drugs

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Asparaginase (Elspar)

What Does It Look Like?

Clear liquid

How Is It Given?

• Intravenous (vein)
• Intra-muscular (muscle)

Why Am I Taking It?

Asparaginase is an anti-cancer drug that stops cell growth by inhibiting its use of protein. This drug is useful in treating leukemia, melanoma, and some lymphomas.

What Side Effects May Occur?

You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.

Low Blood Counts

• Mild anemia is possible. Blood tests will be done to monitor this.
• Call your doctor if you notice any signs of infection or bleeding.

Allergic Reaction

• Symptoms of wheezing, shortness of breath, rash, fever, chills, aches, or swelling may occur.
• Report any signs of a reaction immediately so it can be treated.
• You will be given a smaller test dose of this medicine to make sure you are not allergic to it.

Nausea, Vomiting, Appetite Loss

• Usually mild. Medications will be available to control this symptom.
• Call your doctor if you notice any signs of infection or bleeding. Avoid situations where you might be exposed to people with infections.
• Drink plenty of fluids (2-3 quarts/day) after therapy.

Liver and Pancreas Function

• May damage parts of your liver and pancreas so they do not work properly. Blood tests will be done to monitor their function.
• Call your doctor if you experience severe abdominal pain or if your skin and eyes start to turn yellow.

Nervous System Changes

Drowsiness, headache, tremors, or irritability may occur and should be reported to your doctor.

Special Notes

Changes in your menstrual cycle or sperm counts may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.