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Carmustine (BCNU)

What Does It Look Like?

Clear, colorless liquid

How Is It Given?

Intravenous (vein)

Why Am I Taking It?

Carmustine is an anti-cancer drug that stops cell growth and division. It is used to treat multiple myeloma, Hodgkins and Non-Hodgkins Lymphoma, and tumors of the central nervous system.

What Side Effects May Occur?

You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you experience. The information here does not include all possible side effects; others may occur. Please report problems to your doctor.

Low Blood Counts

  • May cause your white blood cell and platelet counts to drop about 3-5 weeks after treatment. This drop may last for 1-3 weeks.
  • Blood tests will be done to monitor this.
  • Tell your doctor about any signs of infection or bleeding. Avoid situations where you might be exposed to people with infections.

Nausea, Vomiting, Appetite Loss

  • You may have nausea and vomiting starting about 2 hours after treatment and lasting for 4-6 hours. Medications will be available to control these symptoms.
  • You may have a loss of appetite.
  • Drink plenty of fluids (2-3 quarts per day) after therapy.

Skin Changes

  • You may have redness and/or pain at the injection site. Tell the nurse right away if this happens.
  • You may have discoloration of the skin along the vein where the Carmustine was injected.
  • May have a rash or itching.
  • May have facial flushing or swelling of the feet or lower legs.
  • May develop mouth sores. Inspect your mouth daily. Rinse your mouth after meals with a mild salt water solution. Call the doctor if you notice sores or bleeding.

Hair Loss

  • May affect both head and body hair.
  • Hair will grow back after treatment stops.

Special Notes

  • You may notice a decrease in urination. Let the doctor know this. You may also experience diarrhea, shortness of breath or a cough.
  • Changes may occur in your menstrual cycle or sperm count. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.

Use this information in the absence of more specific or personal advice given to you by your doctor, pharmacist or nurse.

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