Chemo Drugs
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Dacarbazine (DTIC)
What Does It Look Like?
Clear to light yellow liquid
How Is It Given?
Intravenous (vein)
Why Am I Taking It?
Dacarbazine is an anti-cancer drug that stops cell growth and division. This drug is used to treat melanoma, soft tissue sarcomas, and Hodgkin's lymphoma.
What Side Effects May Occur?
You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.
Low Blood Counts
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A drop in blood cell counts, especially white blood cells and platelets, occurs about 21-25 days after treatment.
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Blood tests will be done to monitor your blood cell counts.
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Call your doctor about any signs of infection or bleeding. Avoid situations where you may be exposed to people with infections.
Nausea, Vomiting, Appetite Loss
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Medications will be available to control the nausea and vomiting.
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Symptoms may begin 1-4 hours after receiving the drug and continue for 24 hours.
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Restricting food and drink for 3-4 hours before treatment may reduce stomach upset.
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Usually lessens with continued treatment.
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May have a metallic taste in your mouth as Dacarbazine is being given.
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Drink plenty of fluids (2-3 quarts per day) after therapy.
Fever
Hair Loss
Skin Reactions
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Can cause pain at the injection site. Tell the nurse immediately if you notice this.
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Can cause facial flushing.
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Rarely, can cause hives.
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Can cause sores in your mouth. Inspect your mouth daily. Rinse after meals and at bedtime with a mild salt-water solution. Call your doctor if you notice any sores or bleeding in your mouth.
Special Notes
Changes in your menstrual cycle or sperm count may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.