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Chemo Drugs

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Nitrogen Mustard (Mustargen, Mechlorethamine)

What Does It Look Like?

Clear liquid

How Is It Given?

  • Intravenous (vein)
  • Intracavitary (cavity)

Why Am I Taking It?

Nitrogen Mustard is an anti-cancer drug that stops cell growth and division. This drug is used to treat several kinds of cancer, including lymphoma some lung cancers. It is also used to prevent fluid build up around the lungs caused by some cancer cells.

What Side Effects May Occur?

You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.

Low Blood Counts

  • A drop in blood cell counts, especially white blood cells and platelets, occur 7-10 days after treatment.
  • Tell your doctor about any signs of infection or bleeding.
  • Your blood will be drawn occasionally to check your blood counts while you are receiving this drug.
  • Avoid situations where you may be exposed to people with infections.

Vein Irritation, Dark Coloring

  • Use cold, moist packs to reduce soreness.
  • Tell your doctor if pain becomes severe or vein becomes reddened.

Hair Loss

  • May affect both head and body hair.
  • Grows back when drug is stopped.

Nausea, Vomiting

  • May be controlled by taking anti-nausea drug before chemotherapy and routinely for 24 hours after.
  • Usually occurs within 1-3 hours after receiving the drug and nausea may persist for 24 hours.

Special Notes

  • Report any stinging or burning at the needle site to the nurse right away.
  • When this drug is given into a body cavity, you will be asked to change your position in bed every 15 minutes for one hour.
  • Changes in your menstrual cycle or sperm count may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.
  • It is important to drink 2-3 quarts of liquid a day for 72 hours after receiving this drug.

Use this information in the absence of more specific or personal advice given to you by your doctor, pharmacist or nurse.

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