Chemo Drugs

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Thioguanine (6-TG)

What Does It Look Like?

White tablet

How Is It Given?

Oral (mouth)

Why Am I Taking It?

Thioguanine is an anti-cancer drug that stops cell growth and division. This drug is used to treat several kinds of leukemia.

What Side Effects May Occur?

You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.

Low Blood Cell Count

• A drop in blood cell counts, especially white blood cells and platelets, occurs within 2-4 weeks after treatment.
• Tell your doctor about any signs of infection or bleeding.
• Avoid situations where you may be exposed to people with infections.
• Your blood will be drawn occasionally to check your blood counts.

Skin Changes

• May cause tenderness or sores in the mouth.
• Inspect your mouth daily. Rinse after meals and at bedtime with a mild salt water solution.

Liver Function

• May cause a temporary decrease in liver function.

Special Notes

• Changes in your menstrual cycle or sperm count may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.
• Drink 2-3 quarts of liquid daily while receiving this drug.