Chemo Drugs

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Thiotepa (Tespa, TSPA)

What Does It Look Like?

Clear liquid

How Is It Given?

• Bladder irrigation
• Intravenous (vein)
• Intramuscular (muscle)
• Intracavitary (cavity)
• Intrathecal (spinal fluid)

Why Am I Taking It?

Thiotepa is an anti-cancer drug that stops cell growth and division. This drug is used to treat several kinds of cancer, including Hodgkins lymphoma, breast, ovarian, and especially tumors of the bladder.

What Side Effects May Occur?

You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.

Low Blood Cell Count

• A drop in blood cell counts, especially white blood cells and platelets, will occur with treatment.
• Tell your doctor about any signs of infection or bleeding.
• Avoid situations where you may be exposed to people with infections.
• Your blood will be drawn occasionally during treatment to check your blood counts.

Nausea, Vomiting

• These may occur. Medication can be prescribed to control these symptoms.

Skin Changes

• Notify your nurse immediately if you notice any leakage of fluid, redness, burning at vein site.

Special Notes

• When this drug is given into a body cavity, you will be asked to change your position in bed every 15 minutes for one hour.
• Changes in your menstrual cycle or sperm counts may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or father children while taking this drug.